PRODUCTION

Nativa's production is organized in compliance with the European Union Good Manufacturing Practice (EU GMP) for pharmaceutical companies. The company's manufacturing facilities are certified for compliance with GOST R ISO 9001-2008

Nativa invests in the development and purchase of production equipment on an ongoing basis. Our unique high-precision equipment allows us to control quality at all drug production stages.

Harro Höfliger capsule-filling machine for laboratory and industrial use

This high-tech industrial unit is designed for filling and sealing hard gelatin and HPMC capsules. The modern equipment can work with powders that have different physical properties, from microdoses of 1 30 mg to 30–500 mg. The capsule-filling machine has two dosing systems: a drum vacuum pump for microdosing and a compaction system. This type of filling systems is unique as it ensures high dosage accuracy and avoids powder compaction, which is particularly important in the manufacturing of drugs designed for inhalation therapy.

Diosna mixer-homogenizer

The Diosna mixer produces powder with the best aerodynamic properties. It provides maximum yield of the respirable fraction of the active ingredient.

Piconizer spiral jet mill complete with ALPINE Pico PSD disk dosing system

The quality of active substance micronization is crucial for inhalation powder bioavailability. Narrow particle distribution allows us to produce powder with the size of active substance particles ranging from 0.5 µm to 5 µm, which is the most appropriate size for inhalers.
Key advantages include:

  1. Improved grinding chamber geometry;
  2. Optimized static classifier;
  3. Narrow particle size distribution;
  4. Minimum product contact area;
  5. Easy cleaning and validation;
  6. Product output with controlled parameters.

Semi-automatic Pamasol aerosol filling machine

Advanced Swiss technology makes it possible to produce top quality pharmaceutical products. Customers may be confident that they use European quality products. Pamasol equipment fully conforms to GMP requirements and produces high-quality aerosols in the form of solutions and suspensions. The equipment is very reliable and precise.

The unique process production scheme includes vacuum pumping, compression, dosing, and the use of a homogenizer reactor to manufacture high-quality aerosols.